Duncan Muir

Grad Student

Pinney Lab. Duncan completed his B.S. in Data Science and Biochemistry at Northeastern University. Before starting graduate school, he worked in the Structural Biology group at Relay Therapeutics in Cambridge, Massachusetts. There he supported medicinal chemistry efforts through crystallographic fragment screening and developed tools to store and track crystallographic data. As a part of the UCSF Biophysics PhD program he is interested in using high-throughput microfluidic biochemical assays to assemble rich datasets that probe and model the effects of mutations on enzyme activity and stability. He is co-advised by Margaux Pinney.

Lab papers

1. Evolutionary-scale enzymology enables biochemical constant prediction across a multi-peaked catalytic landscape.

   Muir DF, Asper GPR, Notin P, Posner JA, Marks DS, Keiser MJ, Pinney MM. bioRxiv. 2024 Oct 25.